About
Dr. Jochen Steppan's research focuses on the basic science aspects of vascular stiffness, an important predictor of aging-associated cardiovascular morbidity and pulmonary hypertension. In a collaborative effort with a team of cardiovascular biologists and physiologists, Dr. Steppan addresses important pathways of aging, associated changes in nitric oxide signaling, the nitroso-redox milieu, endothelial function, extracellular matrix composition and vascular reactivity. The goal of these studies is to characterize and describe the underlying basic vascular pathophysiology, and importantly to move those studies into the clinical realm to ultimately prevent, halt, or even reverse...